When Screen Reader is enabled, swipe up on the touchpad to request a narrated description of your current status. The Screen Reader can be enabled via the following menu pathway:
Options > Accessibility > Screen Reader and Audio Cues > Screen Reader [Off/On]
When the player character is in a crouched position they may not be able to interact with doors or perform other actions needed to progress. Check your status and attempt to progress by standing from crouching.
If you are receiving a disabled navigation sound, scan for enemies as you may need to eliminate all enemies before progressing. Navigation Assistance will then return.